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. 2023 Feb 24;13:3226. doi: 10.1038/s41598-023-28424-3

Table 3.

Selected panel of human OC cell lines and their relevant mutations, culture conditions, and 96-well plate seeding densities used for in vitro combination cytotoxicity studies.

Cell line Characteristic mutations Culture media Seeding density (cells/well)
OVCAR8 TP5350, BRCA1 hypermethylation51 RPMI, 10% FBS, 100 units/mL penicillin and 100 µg/mL streptomycin 1000
HEYA8 PIK3CA, KRAS, BRAF52 1000
PEO1 TP53, BRCA232 3000
PEO4 TP5332 3000