Fig. 2.

Showing overlap of deregulated metabolic pathways in HD (literature) and cofactor interacting protein-enriched pathway (cofactor network pathway) for B₆, B₁₂ and folate in a Saccharomyces cerevisiae b Mus musculus and c Homo sapiens. d The intersection of metabolic pathways deregulated (literature) in HD and pathways enriched by the cofactor-protein interacting proteins (cofactor network). (e) Common metabolic pathways deregulated showing genes expression and metabolite levels from transcriptomics and metabolomics datasets of HD. The Venn diagrams (a–c) was created using an online tool for multiple list comparator-https://molbiotools.com/listcompare.php