Table 4.
A comparison of the previously reported procedures for the synthesis of chemicals 5a, 6f, and 8a.
Entry | Product | Catalyst | Catalyst loading | Solvent | Temp. (°C) | Time (min) | Yield (%) | Ref. |
---|---|---|---|---|---|---|---|---|
1 | 5a | Cu2(NH2-BDC)2(DABCO) | 40 mg | Solvent-free | r.t | 5 | 96 | This work |
2 | 5a | Cu2(BDC)2(DABCO) | 40 mg | Solvent-free | r.t | 20 | 78 | This work |
3 | 5a | NH4Al(SO4)2.12H2O (Alum) | 20 mg | EtOH | 80 | 120 | 94 | [62] |
4 | 5a | PhB(OH)2 | 5 mol% | H2O/EtOH | Reflux | 30 | 84 | [63] |
5 | 5a | SiO2-Pr-SO3H | 30 mg | H2O/EtOH | Reflux | 15 | 97 | [17] |
6 | 5a | KF/Al2O3 | 250 mg | DMF | r.t | 60–180 | 48 | [60] |
7 | 5a | MPA-MDAZYb | 140 mg | EtOH | 80 | 70 | 90 | [64] |
8 | 5a | ChCl/Urea DESc | 1 mL | ChCl/Urea DESc | 80 | 60–240 | 92 | [65] |
9 | 5a | Amberlyst A21 | 30 mg | EtOH | r.t | 60 | 84 | [66] |
10 | 6f | Sodium Alginate | 10 mol% | EtOH | Reflux | 52 | 93 | [67] |
11 | 6f | MPA-MDAZYb | 140 mg | EtOH | 80 | 40 | 75 | [64] |
12 | 6f | Lipase from Porcine pancreas (PPL) | 30 mg | H2O/EtOH | 35 | 60 | 96 | [68] |
13 | 8a | ChCl/Urea DESc | 1 mL | ChCl/Urea DESc | 80 | 210 | 82 | [65] |
14 | 8a | Sodium Alginate | 10 mol% | EtOH | Reflux | 150 | 90 | [67] |
15 | 8a | nanocrystalline ZnO | 10 mol% | H2O/EtOH | r.t | 150 | 96 | [61] |
a Entries 1–8: Obtained outcomes for the synthesis of molecule5a, Entries 9–11: Obtained outcomes for the synthesis of molecule6f, Entries 12–14: Obtained findings for 8a compound synthesis.
12-Molybdophosphoric acid (MPA), modified dealuminated zeolite Y (MDAZY).
Deep eutectic solvent (DES).