Table 2.

Univariate and multivariate analyses of risk factors for disease-free survival of prostate cancer.

Variable	Univariate analysis HR (95% CI)	P value	Multivariate analysis HR (95% CI)	P value
NRP1 (high/low)	1.65 (1.21–2.23)	0.001	1.45 (1.02–2.06)	0.037
Gleason score (>8/<=8)	2.83 (2.04–3.92)	<0.001	1.86 (1.21–2.85)	0.0046
Age (>65/<=65)	1.12 (0.81–1.54)	0.51	NA	NA
PSA (<=10/>10)	2.64 (1.39–5.03)	0.003	0.89 (0.43–1.88)	0.78
Stage (T4/T3/T2)	2.62 (1.74–3.95)	<0.001	1.07 (0.59–1.95)	0.82
Lymphatic metastasis (yes/no)	1.49 (1.06–2.11)	0.02	0.90 (0.61–1.32)	0.58
Surgical margin (positive/negative)	1.78 (1.33–2.39)	<0.001	1.60 (1.12–2.29)	0.01
Biochemical recurrence (yes/no)	4.56 (3.37–6.15)	<0.001	2.96 (2.07–4.24)	<0.001