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. 2023 Feb 15;16(2):100750. doi: 10.1016/j.waojou.2023.100750

Table 3.

Individual thresholds for food allergens at oral food challenges performed before and immediately after the IgE immuno-adsorption.


Patient 1
Patient 2
Patient 3
Patient 4
Patient 5
pre-IA post-IA pre-IA post-IA pre-IA post-IA pre-IA post-IA pre-IA post-IA
OFC food 1










Food
Baked egg Baked egg Baked milk Lentil Wheat
NOAEL - single dose (mg) 2.088 584.64 20.88 584.64 260 390 58.65 4685.1 4050 6750
LOAEL - single dose (mg) 6.264 NA 62.64 NA 390 NA 175.95 NA 6750 NA
NOAEL - cumulative dose (mg) 2.088 1114.99 29.232 1114.99 447.2 837.2 82.11 7289.16 6311.25 13061.3
LOAEL - cumulative dose (mg)
8.352
NA
91.872
NA
837.2
NA
258.06
NA
13061.3
NA
OFC food 2










Food
Baked milk Baked milk Hazelnut Hazelnut Baked milk
NOAEL - single dose (mg) 1.3 130 0 39 69 2070 13.8 2070 0 390
LOAEL - single dose (mg) 3.9 260 1.3 130 138 NA 69 NA 1.3 NA
NOAEL - cumulative dose (mg) 1.3 187.2 0 57.2 82.8 4222.8 13.8 4222.8 0 837.2
LOAEL - cumulative dose (mg) 5.2 447.2 1.3 187.2 220.8 NA 82.8 NA 1.3 NA

List of abbreviations: IA, IgE-immunoapheresis; LOAEL, Lowest Observed Adverse Effect Levels; NA, Not Applicable; NOAEL, No Observed Adverse Effect Level