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. 2023 Feb 15;24(4):3925. doi: 10.3390/ijms24043925

Figure 3.

Figure 3

Conditional Q-Q plots showed cross-trait enrichment between POAG/IOP and BMI. (A) Conditional Q-Q plot of nominal—log10(p) for SNPs association with POAG as a function of statistical significance for SNPs association with BMI at the predefined stratum of p values. The lines with sharp leftward deviated tails showed the true associations between POAG and BMI. (B) Conditional Q-Q plot of nominal—log10(p) for SNPs association with BMI as a function of statistical significance for SNPs association with POAG at the predefined stratum of p values. The lines with sharp leftward deviated tails showed the true associations between BMI and POAG. (C) Conditional Q-Q plot of nominal—log10(p) for SNPs association with IOP as a function of statistical significance for SNPs association with BMI at the predefined stratum of p values. The lines with sharp leftward deviated tails showed the true associations between IOP and BMI. (D) Conditional Q-Q plot of nominal—log10(p) for SNPs association with BMI as a function of statistical significance for SNPs association with IOP at the predefined stratum of p values. The lines with sharp leftward deviated tails showed the true associations between BMI and IOP.