Table 1.

Representative strains, classic variation, and pathogenicity of each TGEV genotype.

Strain	Isolate	Variation	Pathogenicity	Genbank ID	Reference
Purdue	Virulent Purdue	NA	Virulent	DQ811789.2	[6,68]
Purdue	Purdue P115	S protein nt1123–1128 deletion	Attenuated	DQ811788.1	[6,68]
Purdue	PUR46-MAD	S protein nt1123–1128 deletion	Attenuated	NC_038861.1	[6,23]
Purdue	SHXB	S protein nt1123–1128 deletion	Virulent	KP202848.1	[103,104]
Between Purdue and Miller	AHHF	S protein nt2386–2388 deletion	Virulent	KX499468.1	[6,9]
Miller	H16	ORF3 −75–−60nt and 195–223nt deletion, S protein nt2386–2388 deletion	Virulent	FJ755618.2	[6,9]
Miller	Miller M60	ORF3 −75–−60nt and 195–223nt deletion, ORF3b 405–935nt deletion	Attenuated	DQ811786.2	[6,68]
Miller	Miller M6	ORF3 −75–−60nt and 195–223nt deletion	Virulent	DQ811785.1	[6,68]
Miller	JS2012	ORF3 −75–−60nt and 195–223nt deletion	Virulent	KT696544.1	[6,7]
Miller	attenuated H	ORF3 −75–−60nt and 195–223nt deletion, S nt2386–2388 deletion	Attenuated	EU074218.2	[9]

The evaluation of the virulence of the virus is based on the virulence of the virus as described by the author in the first report: if the individual challenge experimental piglets die or the pathological sections of the small intestine show severe lesions, this strain is a virulent strain.