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. 2023 Feb 20;15(2):709. doi: 10.3390/pharmaceutics15020709

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Response-surface-methodology plot for the effect of formulation factors (X1, X2, and X3) on the entrapment efficiency percentage (Y1). (A) Effect of sodium alginate concentration and cross-linker concentration on the entrapment efficiency percentage (Y1); (B) effect of sodium alginate concentration and sesame oil concentration on the entrapment efficiency percentage (Y1); and (C) effect of cross-linker concentration and sesame oil concentration on the entrapment efficiency percentage (Y1).