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. 2023 Jan 22;12(2):174. doi: 10.3390/pathogens12020174

Table 3.

The list of genes that showed upregulated proteins in N. fowleri trophozites and cysts.

Upregulated Proteins in N. fowleri Trophozoites log FC
Luminal-binding protein 14.309
Lysosomal Pro-X carboxypeptidase 7.017
Chaperone protein 4.349
12-oxophytodienoate reductase 1 4.344
Probable alpha-L-glutamate ligase 4.181
fatty acid desaturase 4.120
Cytoskeleton-associated protein 3.280
Tubulin alpha-6 chain 2.659
Actin 2.115
Microtubule-associated protein 1.996
Upregulated Proteins in N. fowleri Cysts log FC
Uridine kinase 13.526
Calpain-5 8.641
Translin-associated factor X-interacting protein 7.394
Gag-Pol polyprotein 6.912
Profilin 6.813
Probable E3 ubiquitin-protein ligase 6.707
Serine/threonine-protein kinase 6.683
LisH domain-containing protein 5.032
Phospholipid-transporting ATPase 4.970
EF-hand domain-containing family member C2 4.579
Kinesin-like calmodulin-binding protein 4.429
Probable glycerol-3-phosphate dehydrogenase(mt) 4.327
Sphingosine-1-phosphate lyase 4.285
Nitrile-specifier protein 4.174