| AKT/PKB | serine/threonine kinase/protein kinase B |
| AMBRA1 | Autophagy and beclin 1 regulator 1 |
| AMPK | 5′ Adenosine-monophosphate-activated protein kinase |
| APC | Adenomatous polyposis coli |
| ATG | Autophagy-related genes or proteins |
| BAX | Bcl-2-associated X protein |
| BECN1 | Beclin1, a mammalian ortholog of the yeast Atg6 |
| BEST4 | Bestrophin 4 |
| BNIP3 | Bcl-2-interacting protein 3 |
| BNIP3L | Bcl-2/adenovirus E1B 19kDa protein-interacting protein 3-like |
| BRAF | Proto-oncogene B-Raf; encodes protein called B-Raf |
| CCL2/MCP-1 | Chemokine (C-C Motif) ligand 2/monocyte chemoattractant protein 1 |
| CCL8/MCP-2 | Chemokine (C-C Motif) ligand 8/monocyte chemoattractant protein 2 |
| C/E/I/M(SCs) | Cancer/embryonic/intestinal/mesenchymal stem cells |
| CD | Crohn’s disease |
| CI | Confidence interval |
| CIMP | CpG island methylator phenotype |
| CIN | Chromosomal instability |
| c-MET | Tyrosine-protein kinase Met/hepatocyte growth factor receptor (HGFR) |
| c-Myc | Proto-oncogene protein; transcription factor |
| CQ | Chloroquine |
| CRC | Colorectal cancer |
| CSCs | Cancer stem cells |
| c-Src | Src proto-oncogene, non-receptor tyrosine kinase |
| DECP1 | Double FYVE-containing protein 1 or ZFYVE1 protein |
| EGF/EGFR | Epidermal growth factor/EGF receptor (HER1 in humans) |
| eIF4A3 | Eukaryotic initiation factor 4A-III |
| ERK1/2 | Extracellular signal-regulated kinase 1/2 |
| FAK | Focal adhesion kinase or protein tyrosine kinase 2 |
| FOXO | Forkhead box protein class O |
| GAPs | Goblet cell-associated antigen passage |
| GH/GH-R | Growth hormone/GH-receptor |
| GLP-2 | Glucagon-like peptide 2 |
| GNPTAB | N-acetylglucosamine-1-phosphotransferase subunits alpha/beta |
| GSK-3β | Glycogen synthase kinase-3β |
| HIF-1 | Hypoxia-inducible factor 1 |
| IBD | Inflammatory bowel diseases |
| IECs | Intestinal epithelial cells |
| IGF-1, -2 | Insulin growth factor 1, -2 |
| IGF-1R, -2R | IGF receptor type I, type II |
| IGF-BPs | IGF-binding proteins |
| IR-A | Isoform A of the insulin receptor |
| IRS-1/2 | Insulin receptor substrate 1/2 |
| JAK | Janus kinase |
| KLF4 | Gut-enriched Kruppel-like factor 4; zinc-finger transcription factor |
| KRAS | Kirsten rat sarcoma virus; encodes protein called K-Ras |
| LAMP2 | Lysosome-associated membrane protein 2 |
| (M)LC3B/MAP2 | Microtubule-associated protein 1A/1B light chain 3B/protein 2 |
| LKB1 | Liver kinase B1; serine/threonine protein kinase (STK11) |
| lncRNAs | Long non-coding RNAs |
| LOI | Loss of imprinting |
| MAPK | Mitogen-activated protein kinase |
| MEFs | Mouse embryonic fibroblasts |
| MEK1/2 | Mitogen-activated protein kinase (MAP2K, MEK, MAPKK) |
| MetS | Metabolic syndrome |
| MOI | Maintenance of imprinting |
| MSI-H | High microsatellite instability |
| MSS | Microsatellite stable |
| mTORC1/2 | Mammalian target of rapamycin complex 1/complex 2 |
| NADPH | Nicotinamide adenine dinucleotide phosphate oxidase |
| NANOG | Homebox protein, transcription factor |
| NF-κB | Nuclear factor-kappa B |
| NRF-1/2 | Nuclear respiratory factor 1/2 |
| OCT-4 | Octamer-binding transcription factor 4 |
| OS | Overall survival |
| PARP1 | Poly [ADP-ribose] polymerase 1 |
| PGDF | Platelet-derived growth factor |
| PI3K | Phosphatidylinositol-3-kinase |
| PIK3CA | Gene encoding phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| PINK1 | PTEN-induced kinase 1 |
| PLCs | Paneth-like cells |
| PKCα/PRKCA | Protein kinase Cα |
| PPAR | Peroxisome proliferator-activated receptor |
| PSCs | Pluripotent stem cells |
| PTEN | Phosphatase and tensin homolog deleted on chromosome ten |
| Raf-1 | Proto-oncogene serine/threonine protein kinase |
| Raptor | Regulatory-associated protein of mTOR |
| RAS | Oncogene “Rat sarcoma virus” from three Ras genes: HRAS, KRAS and NRAS |
| ROS | Reactive oxygen species |
| SATB2 | SATB homeobox 2; DNA-binding protein |
| SGK-1 | Serine/threonine-protein kinase/serum and glucocorticoid-regulated kinase 1 |
| SHC | SHC-transforming protein 1 encoded by the SHC gene |
| SIRT1 | NAD-dependent deacetylase sirtuin 1, a mammalian homologue of silent information regulator 2 of the yeast Saccharomyces cerevisiae |
| SLITs/ROBOs | SLIT glycoproteins and their roundabout receptors |
| SNP | Single nucleotide polymorphism |
| SNX9, -18,-33 | Sorting nexin9, -18, -33 |
| SOD3 | Superoxide dismutase 3 |
| SOX2 | Transcription factor 2, known also as sex-determining region Y (SRY)-box 2 |
| STAT3 | Signal transducer and activator of transcription 3 |
| TCGA | The cancer genome atlas |
| TGF-α, β | Tumor growth factor α, β |
| TLRs | Toll-like receptors |
| TME | Tumor microenvironment |
| TP53 | Tumor gene/protein 53 |
| UC | Ulcerative colitis |
| ULK1/2 | Unc-51 like autophagy activating kinase |
| uPA/uPAR | Urokinase-type plasminogen activator/receptor |
| Wnt | Gene wingless + integrated or int-1 |