Table 4.
Between treatment effects [a] (CEE/MPA vs. E2/P FC ratios) from Q-PCR of the thirteen genes affecting the IPA function “breast carcinoma”. [b]: Literature findings concerning increased expression of the respective gene on “breast carcinoma”.
| Affymetrix ID | Genes | Predicted Effect [a] | Fold Change Ratio | Findings [b] |
|---|---|---|---|---|
| 7937020 | PRL | Increased | 13.60 | Increases |
| 7980908 | MKi-67 | Affected | 5.307 | Affects |
| 8089771 | FBLN5 | Affected | 3.884 | Affects |
| 7912145 | CD80 | Affected | 3.456 | Affects |
| 7965873 | TNFRSF9 | Increased | 2.491 | Increases |
| 8122843 | IGF1 | Affected | 1.708 | Affects |
| 8023646 | ESR1 | Increased | 1.591 | Increases |
| 8135594 | BCL-2 | Increased | 1.587 | Increases |
| 7951165 | CAV1 | Affected | 1.518 | Affects |
| 8155849 | PGR | Affected | 1.226 | Affects |
| 8105111 | ANXA1 | Increased | 1.062 | Increases |
| 7956120 | FBXO4 | Increased | −1.290 | Decreases |
| 7956120 | ERBB3 | Decreased | −1.741 | Increases |
Adapted from IPA database, Ingenuity Systems.