Table 1.
Characterization of unloaded nanoemulsion (NERO), 1 mg/mL kojic dipalmitate (KDP)-loaded nanoemulsion (NERO1KDP), and 2 mg/mL KDP-loaded nanoemulsion (NERO2KDP).
| Formulation | NERO | NERO1KDP | NERO2KDP |
|---|---|---|---|
| Average size (nm) (laser diffraction) | 123 ± 2 | 117 ± 2 | 122 ± 5 |
| Span value | 0.842 ± 0.009 | 0.827 ± 0.003 | 0.918 ± 0.135 |
| Average size (nm) (dynamic light scattering) | 72 ± 2 | 74 ± 1 | 73 ± 1 |
| PDI | 0.281 ± 0.020 | 0.269 ± 0.004 | 0.273 ± 0.004 |
| Zeta potential (mV) | −8.57 ± 1.92 | −9.44 ± 0.53 | −10.24 ± 0.66 |
| Ph | 6.7 ± 0.1 | 6.8 ± 0.1 | 6.7 ± 0.1 |
| Density (g/mL) | 0.9983 ± 0.0002 | 0.9975 ± 0.0005 | 0.9977 ± 0.0007 |
| KDP content (%) | - | 101.29 ± 1.62 | 96.67 ± 4.96 |
| Incorporation efficiency (%) | - | 97.79 ± 2.01 | 97.60 ± 1.93 |