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. 2023 Jan 18;15(2):320. doi: 10.3390/pharmaceutics15020320

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Preparation of oligonucleotide-peptide conjugates. (A) Postsynthetic conjugation of a thiol-oligonucleotide with a peptide by a maleimide moiety [124]. (B) Stepwise method for the synthesis of oligonucleotide-peptide conjugates on a solid support [113,114,115,116].