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Solvent channel, family 2 channels and active site of P450s. Channels are shown as connected spheres with different colors: cyan (2a), orange (2ac), purple (2b), blue (2c), wheat (2d), red (2e) and yellow (2f). Helix I and heme of P450s are labeled. (A) CYP6A36, (B) CYP6D10 and (C) CYP4S24. Glutamate 313 and Threonine 317 are also labeled.
