Table 3.
Tumorigenic potential of PITPα +/+ and −/− ES cells Athymic nude mice were injected subcutaneously in the hind flank with 107 ES cells suspended in 0.2 ml of PBS/glucose. The tumors that formed were surgically harvested after 3 wk and weighed. Values represent the mean and standard error derived from analyses of all tumors in a given set.
| Injected cells | Mice with tumors/ mice injected | Tumor mass (g) |
|---|---|---|
| R1 PITPα +/+ | 7 /7 | 0.88 ± 0.56 |
| R1 PITPα −/− | 10 /10 | 0.86 ± 0.43 |
| AB1 PITPα +/+ | 4 /4 | 1.27 ± 0.13 |
| AB1 PITPα −/− | 10 /10 | 1.48 ± 0.45 |