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Cytokine signaling mediated by Jak-STAT. Each cytokine interacts with a particular combination of Jak-STAT molecules. Created with BioRender.com (accessed on 14 January 2023). Abbreviations: Jak, Janus kinase; STAT, signal transducer and activator of transcription; Tyk2, tyrosine kinase 2; IFN, interferon; IL, interleukin; EPO, erythropoietin; GH, growth hormone; TPO, thrombopoietin; GM-CSF, granulocyte macrophage colony-stimulating factor.
