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. 2023 Feb 13;24(4):3747. doi: 10.3390/ijms24043747

Table 1.

IC50 values of cell response to OHT or ICI as compared using one-way ANOVA. OHT, 4-hydroxytamoxifen; ICI, ICI182,780.

Cell Line OHT ICI
IC50 (nM) MCF7-WT 2.26 ± 0.90 0.76 ± 0.06
MCF7-ERβ1 0.59 ± 0.09 0.55 ± 0.03
MCF7-ERβ2 2.46 ± 0.35 0.96 ± 0.08
p value MCF7-WT vs. MCF7-ERβ1 0.046 0.025
MCF7-WT vs. MCF7-ERβ2 0.794 0.027
MCF7-ERβ1 vs. MCF7-ERβ2 0.030 0.000