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. 2023 Jan 31;13(2):388. doi: 10.3390/life13020388

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Representative light micrographs of gastric tissue samples. Normal morphology in gastric mucosa with surface epithelium and gland structure in the control group (A). Severe damage in the surface epithelium, glandular degeneration, hemorrhage, and inflammatory cell infiltration in the INDO group (B,C). Mild epithelial damage, glandular degeneration, and inflammatory cell infiltration in the FA100 group (D). Slight mucosal damage with mild glandular degeneration in the FA250 group (E). Moderate mucosal and glandular degeneration in the FA500 group (F). INDO: Indomethacin; FA100: Indomethacin+ Ferulic Acid 100 mg/kg; FA250: Indomethacin + Ferulic Acid 250 mg/kg; FA500: Indomethacin + Ferulic Acid 500 mg/kg. epithelial damage (arrow), inflammatory cell infiltration (arrowhead), hemorrhage (h) glandular degeneration (asterisk). H&E staining.