Table 2.

Examples of drugs that were originally used in women but show anticancer activity in prostate cancer.

Drug Class	Drug	Original Use	Anticancer Mechanism	References
Selective estrogen receptor modulator	Ormeloxifene	Oral contraceptive	Inhibit EMT by repressing N-cadherin and β-catenin	[2,5]
Antiprogesterone	Mifepristone	Pregnancy termination	Suppression via blocking cell surface progesterone receptors; induction of TFG-β-1