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. 2002 Mar;13(3):782–794. doi: 10.1091/mbc.01-10-0512

Table 9.

Orphan open reading frames

Locus Vacuolar phenotype(s) CPY secretion
YCL016c 50%B +
YDR200c 70%B +
YDR223w 10%B 40%E +
YDR433w 80%B +
YEL044w 40%B 40%D +++
YER083c 30%B 30%C 30%E +
YGL024w 75%B
YGL223c 90%B +++
YJL075c 40%B
YJL184w 40%C 20%D +
YLL002w 60%B +
YLR091w 90%C
YLR204w 70%D +
YLR261c 60%B 10%C ++
YLR320w 50%B +
YLR322w 25%B 25%C +
YML013c-A 35%B 35%C ++
YMR269w 85%B
YNL080c 70%B +
YNL281w 70%B +
YNL297c 60%B +
YOL008w 50%B
YOL035c 60%B +
YOL050c 70%B +
YOL063c 50%B +
YOR068c 90%B +++
YOR359w 25%B 25%C +
YPL055c 50%B ++

Three genes (YLR320w, YNL281w, and YOR068c) are adjacent to genes that are also required for normal vacuole morphology. Further analysis will be required to determine whether these deletions act by altering the expression level of an adjacent gene.