Table 4.
Faecal microbial quantification after 24 h of fermentation in neurotypical children.
| NC | INU | scFOS | PO | PE | Overall p | |
|---|---|---|---|---|---|---|
| Total bacteria | 9.83 (9.77–9.99) |
10.34 (10.26–10.37) a |
10.33 (10.27–10.41) a |
10.40 (10.27–10.47) *,a |
10.41 (10.30–10.60) *,a |
0.013 |
| Bifidobacterium spp. | 8.96 (8.60–9.47) |
10.17 (9.88–10.30) *,a |
10.23 (10.15–10.33) *,a |
9.90 (9.34–10.00) a |
9.72 (9.23–10.18) a |
0.004 |
| Lactobacillus group | 5.09 (4.76–6.31) |
5.43 (4.75–6.40) |
5.31 (4.61–6.35) |
5.35 (4.80–6.29) |
5.21 (4.88–6.52) |
0.998 |
| C. perfringens group | 6.99 (6.54–7.21) |
7.27 (6.74–7.93) |
7.18 (6.70–7.79) |
7.25 (6.69–7.56) |
7.42 (6.79–8.03) |
0.563 |
| Bacteroides spp. | 9.16 (9.04–9.44) |
9.85 (9.73–10.10) a |
9.67 (9.59–10.08) a |
10.00 (9.60–10.28) a |
9.82 (9.51–10.21) a |
0.033 |
| F. prausnitzii | 8.24 (6.97–8.49) a |
8.67 (8.11–8.88) |
8.62 (8.07–8.86) |
9.08 (8.36–9.20) a |
8.80 (8.52–9.25) |
0.050 |
| Prevotella spp. | 7.69 (7.44–8.52) |
9.61 (7.87–10.05) |
9.39 (7.83–9.92) |
9.35 (7.12–10.09) |
9.30 (8.25–9.98) |
0.431 |
| A. muciniphila | 4.80 (4.65–8.23) |
4.81 (4.25–7.99) |
4.76 (4.18–8.20) |
4.74 (4.55–8.26) |
4.67 (4.45–8.32) a |
0.981 |
Values are expressed as median and Q1–Q3 quartiles for non-parametric data; a: significantly different compared to t = 0 h for neurotypical children (Wilcoxon signed-rank test); *: significantly different compared to NC after 24 h of fermentation for neurotypical children (Kruskall–Wallis test with pairwise comparisons). Quantitative PCR (qPCR); log10 copies of 16S rRNA gene mL−1 of sample.