Figure 1. Recruitment, Randomization, and Follow-up of Participants in a Trial of Verapamil vs Placebo for the Preservation of Beta Cell Function in Children and Adolescents With Newly Diagnosed Type 1 Diabetes.

^aRandomization was stratified by site with a permuted block design. Intensive diabetes management included an automated insulin delivery system.

^bHad at least 1 analyzable area under the curve value for C-peptide level (a measure of pancreatic beta cell function) stimulated by a mixed-meal tolerance test. One participant in the placebo group who dropped out immediately after randomization before completing the baseline mixed-meal tolerance test was not included in the primary analysis.