Table 3.
Risk Factors | All Patients (n = 224) |
No IFI (n = 198) |
IFI (n = 26) |
p-Value | Missing Data (n/Total) | |
---|---|---|---|---|---|---|
Preoperative risk factors | ||||||
MELD Score > 30 | 20 (8.9) | 16 (8.1) | 4 (15.4) | 0.263 | 7/224 | |
Fungal colonization at baseline | 15 (6.7) | 10 (5.1) | 5 (19.2) | 0.019 | 0/224 | |
Anti-infective pretreatment | 30 (13.4) | 25 (12.6) | 5 (19.2) | 0.360 | 0/224 | |
Pretransplant serum creatinine > 2 mg/dL | 21 (9.4) | 19 (9.6) | 2 (7.7) | 1.000 | 0/224 | |
Intraoperative risk factors | ||||||
Choledochojejunostomy, any time | 24 (10.7) | 15 (7.6) | 9 (34.6) | <0.001 | 1/224 | |
Choledochojejunostomy, primary | 15 (6.7) | 11 (5.6) | 4 (15.4) | 0.080 | 1/224 | |
Transplantation time > 11 h | 4 (1.8) | 4 (2.0) | 0 (0.0) | 1.000 | 2/224 | |
Intraoperative blood transfusion > 40 PRBC | 2 (0.9) | 1 (0.5) | 1 (3.8) | 0.220 | 2/224 | |
Split liver transplantation | 6 (2.7) | 3 (1.5) | 3 (11.5) | 0.022 | 0/224 | |
Donor-derived infection | 7 (3.1) | 2 (1.0) | 5 (19.2) | <0.001 | 0/224 | |
High-urgency transplantation | 9 (4.0) | 6 (3.0) | 3 (11.5) | 0.079 | 0/224 | |
Postoperative risk factors | ||||||
Bile leak | 34 (15.2) | 22 (11.2) | 12 (46.2) | <0.001 | 1/224 | |
Choledochojejunostomy, secondary | 9 (4.0) | 4 (2.0) | 5 (19.2) | 0.001 | 1/224 | |
Relaparotomy, any reason | 77 (34.4) | 57 (28.8) | 20 (76.9) | <0.001 | 1/224 | |
Relaparotomy, bile leak related | 29 (12.9) | 19 (9.6) | 10 (38.5) | <0.001 | 1/224 | |
Relaparotomy, not bile leak related | 48 (21.4) | 38 (19.2) | 10 (38.5) | 0.039 | 1/224 | |
Early re-transplantation | 6 (2.7) | 2 (1.0) | 4 (15.4) | 0.002 | 0/224 | |
Posttransplant dialysis | 99 (44.2) | 80 (40.4) | 19 (73.1) | 0.003 | 0/224 | |
CMV viremia | 64 (28.6) | 54 (27.3) | 10 (38.5) | 0.252 | 0/224 |
Abbreviations: IFI: invasive fungal infection; PRBC: packed red blood cells; MELD: model of end-stage liver disease; CMV: cytomegalovirus; RRT: renal replacement therapy.