Table 2.
Histopathologic characteristics of liver lesions at explant pathology
| Non-treated lesions | |||||
| HCC | cHCC-CCA | CCA | Benign | Total | |
| Number of lesions (%) | 104 (88.9) | 2 (1.7) | 1 (0.9) | 10 (8.5) | 117 (100) |
| Mean size ± SD (range, cm) | 1.3 ± 0.63 (0.5–3.5) | 1.5 (0.5–2.5) | 1.0 (NA) | 1.3 ± 0.8 (0.6–32) | 1.3 ± 0.65 (0.5–3.5) |
| Number in subgroups (%) | |||||
| 0.5–0.9 cm | 34 (29.1) | 1 (0.9) | – | 4 (3.4) | 39 (33.3) |
| 1–1.9 cm | 56 (47.8) | – | 1 (0.9) | 4 (3.4) | 61 (52.1) |
| ≥ 2 cm | 14 (12) | 1 (0.9) | – | 2 (1.7) | 17 (14.6) |
| Differentiation (%) | |||||
| Well | 9 (7.7) | – | – | – | 9 (7.7) |
| Moderately | 92 (78.6) | 1 (0.9) | 1 (0.9) | – | 94 (80.3) |
| poorly | 3 (2.6) | 1 (0.9) | – | – | 4 (3.4) |
| Treated observations | |||||
| Viable HCC | Viable cHCC-CCA | Non-viable HCC | Total | ||
| Number of lesions (%) | 42 (31.3) | 2 (1.5) | 90 (67.2) | 134 (100) | |
| Whole mean size ± SD (range, cm) | 2.9 ± 2.0 (0.6–10.5) | 3.0 (2.0–4.0) | 2.4 ± 1.3 (0.2–6.0) | 2.6 ± 1.6 (0.2–10.5) | |
| Viable mean size ± SD (range, cm) | 1.6 ± 1.3 (0.1–5.5) | 1.1 (0.5–1.6) | 0 ± 0 | 1.5 ± 1.2 (0.1–5.5) | |
| Number in subgroups (%) | |||||
| < 2 cm | 32 (23.9) | 2 (1.5) | 36 (26.8) | 70 (52.2) | |
| ≥ 2 cm | 10 (7.5) | – | 54 (40.3) | 64 (47.8) | |
| Differentiation states (%) | |||||
| Well | 4 (3) | – | – | 4 (3) | |
| Moderately | 36 (26.8) | – | – | 36 (26.8) | |
| poorly | 2 (1.5) | 2 (1.5) | – | 4 (3) | |
HCC hepatocellular carcinoma, cHCC-CCA combined hepatocellular-cholangiocarcinoma, CCA cholangiocarcinoma, SD standard deviation