Table 4.
Diagnostic performance of CECT and EOB-MRI for detecting viable HCC with corresponding histopathologic abnormality
| Size | CECT | EOB-MRI | P-value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Se | Sp | NPV | PPV | Acc | Se | Sp | NPV | PPV | Acc | Sen | Sp | ||
| overall | R1 | 58.3 (21/36) | 86.6 (58/67) | 79.5 (58/73) | 70 (21/30) | 76.7 (79/103) | 66.7 (22/33) | 88.5 (54/61) | 83.1 (54/65) | 75.9 (22/29) | 80.9 (76/94) | ||
| R2 | 54.5 (18/33) | 91.7 (66/72) | 81.5 (66/81) | 75 (18/24) | 80 (84/105) | 60 (21/35) | 95.8 (69/72) | 83.1 (69/83) | 87.5 (21/24) | 84.1 (90/107) | |||
| Pooled | 56.5 | 89.2 | 63.2 | 92.5 | 0.312 | 0.312 | |||||||
| < 2 cm | R1 | 81 (17/21) | 50 (9/18) | 69.2 (9/13) | 65.4 (17/26) | 66.7 (26/39) | 87.5 (14/16) | 50 (7/14) | 77.8 (7/9) | 66.7 (14/21) | 70 (21/30) | ||
| R2 | 66.7 (10/15) | 75 (12/16) | 70.6 12/17) | 71.4 10/14) | 71 (22/31) | 82.4 (14/17) | 83.3 (10/12) | 76.9 (10/13) | 87.5 (14/16) | 82.8 (24/29) | |||
| Pooled | 75 | 61.8 | 84.8 | 65.4 | 0.037 | 0.037 | |||||||
| ≥ 2 cm | R1 | 26.7 (4/15) | 100 (49/49) | 81.7 (49/60) | 100 (4/4) | 82.8 (53/64) | 47.1 (8/17) | 100 (45/45) | 83.3 (45/54) | 100 (8/8) | 85.5 (53/62) | ||
| R2 | 44.4 (8/18) | 96.4 (54/56) | 84.4 54/64) | 80 8/10) | 83.8 (62/74) | 38.9 (7/18) | 98.3 (59/60) | 84.3 (59/70) | 87.5 (7/8) | 84.6 (66/78) | |||
| Pooled | 36.4 | 98.1 | 42.9 | 99 | 0.504 | 0.504 | |||||||
Data are percentages, with numerators and denominators in parentheses
Acc accuracy, CECT contrast-enhanced computed tomography, EOB-MRI Gadoxetic acid-enhanced MRI, NPV negative predictive value, PPV positive predictive value, R1 reader 1, R2 reader 2, Se sensitivity, Sp specificity