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. 2023 Feb 25;21:153. doi: 10.1186/s12967-023-04009-6

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — LINC00543 promotes EMT in CRC cells. a The morphologies of CRC cells in response to LINC00543 manipulation (scale bar = 25 μm) b qRT-PCR and c western blot analysis of E-cadherin and Vimentin in the SH and LINC00543 cells. d E-cadherin, N-cadherin, and Vimentin expression in the SH and LINC00543 cells were determined by immunofluorescence staining (scale bar = 25 μm). e and f The expression of EMT-related markers in the NC and SH group mice. g The expression of EMT-related markers in the NC and SH group mice was determined by immunohistochemistry (IHC) (scale bar = 100 μm)