Table 3.
Comparison of MET fusion sites of enrolled lung cancer patients according to the status of EGFR/ALK mutations
| Fusion sites of MET | Primary MET fusions (n = 38) | Acquired MET fusions (n = 18) | ||
|---|---|---|---|---|
| Number | Location | Number | Location | |
| Introns | 25 | NA | 10 | NA |
| Exons | 13 | 6 | ||
| Exon2 | 1 | Extracellular | / | / |
| Exon3 | / | / | 2 | Extracellular |
| Exon4 | / | / | 1 | Extracellular |
| Exon6 | / | / | 1 | Extracellular |
| Exon10 | 1 | Extracellular | / | / |
| Exon11 | 1 | Extracellular | 1 | Extracellular |
| Exon12 | 2 | Extracellular | / | / |
| Exon13 | 1 | Transmembrane | / | / |
| Exon14 | 2 | Cytoplasmic | / | / |
| Exon15 | 1 | Cytoplasmic | / | / |
| Exon17 | 1 | Cytoplasmic | ||
| Exon19 | 2 | Cytoplasmic | / | / |
| Exon21 | 2 | Cytoplasmic | / | / |
| NA | / | / | 2 | / |
NA not applicable