Effect of curcumin and GT863 on cell-membrane potential and electrical resistance of the cell membrane. (A) The membrane potential in Aβo-stimulated SH-SY5Y cells was evaluated using DiBAC4(3). The membrane potential in SH-SY5Y cells exposed to 5 µM Aβo and treated with Aβo + 1 µM curcumin and Aβo + 1 µM GT863 (n = 4, Tukey’s test). (B) Resting-membrane potential was measured in SH-SY5Y cells treated with 5 µM Aβo, curcumin, and GT863 by patch-clamp recording. ## p < 0.01 vs. Aβo group. (C) Electrical resistance of the membrane was measured in SH-SY5Y cells treated with 5 µM Aβo, curcumin, and GT863 by patch-clamp recording. # p < 0.05 vs. Aβo group. ## p < 0.01 vs. Aβo group. The p-values in ANOVA were 0.0001. Each value expresses the mean ± S.E.M. of at least 3 independent experiments.