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Independent and dependent variables created based on CCD for nanoemulsion formulation.
| Independent Variables | Level | Dependent Variables | Aim | ||||
|---|---|---|---|---|---|---|---|
| Low (−1) | Medium (0) | High (+1) | |||||
| X 1 | Homogenisation time (min) | 10 | 7.5 | 5 | Y 1 | Particle size (nm) | Reduction |
| X 2 | Ultrasonication time (min) | 20 | 15 | 10 | Y 2 | PDI | Reduction |
| X 3 | Amplitude (%) | 70 | 60 | 50 | |||
