AAE	Annurca apple polyphenolic extract
ACS	acute coronary syndrome
ASCVD	atherosclerotic cardiovascular disease
ATP	adenosine triphosphate
CAP	Cholesterol and Pharmacogenetic
CE	capillary electrophoresis
CPT-1	carnitine palmitoyltransferase I
CVD	cardiovascular disease
FH	familial hypercholesterolemia
FT-ICR	Fourier transform-ion cyclotron resonance
GC	gas chromatography
GlycA	glycoprotein acetylation
GSK-3β	glycogen synthase kinase-3β
HDL	high-density lipoprotein
HK-2	hexokinase 2
HMG-CoA	3-hydroxy-3-methyl-glutaryl-coenzyme A
IDL	intermediate-density lipoprotein
LC	liquid chromatography
LDL	low-density lipoprotein
LDL-C	low-density lipoprotein cholesterol
Lp(a)	lipoprotein(a)
MRM	multiple reaction monitoring
MS	mass spectrometry
NIST	National Institute of Standards and Technology
NMR	nuclear magnetic resonance
NO	nitric oxide
NOS	nitric oxide synthase
PAH	pulmonary arterial hypertension
PCSK9	proprotein convertase subtilisin/kexin type 9
PPARα	peroxisome proliferator-activated receptor alpha
PUFAs	polyunsaturated fatty acids
Q-TOF	quadrupole-time of flight
ROS	reactive oxygen species
SNP	single nucleotide polymorphism
SREBP-1c	sterol regulatory element-binding protein 1c
TC	total cholesterol
TGs	triglycerides
TOF	time of flight
UHPLC	ultra-high-performance liquid chromatography
UPLC	ultra-performance liquid chromatography
VLDL	very-low-density lipoprotein
WHHL	Watanabe heritable hyperlipidemic