Table 1:
Effect of chlorine (CI2) exposure on the numbers of alveolar macrophages expressing inflammatory and oxidative stress markers.
| CTL | CI2 | |
|---|---|---|
| COX-2 | 4.6 ± 1.5 | 9.7 ± 3.5 |
| iNOS | 1.1 ± 0.5 | 2.2 ± 0.4 |
| MR | 4.0 ± 0.5 | 5.0 ± 0.6 |
| Ym-1 | 7.8 ± 0.5 | 9.0 ± 1.0 |
| HO-1 | 3.6 ± 0.2 | 5.2 ± 0.6a |
| Catalase | 0.6 ± 0.2 | 2.8 ± 0.6a |
Sections of the left lobe were prepared 24 h after exposure of mice to air control (CTL) or CI2. Numbers of alveolar macrophages staining positively for cyclooxygenase (COX)-2, inducible nitric oxide synthase (iNOS), mannose receptor (MR), Ym-1, heme oxygenase (HO)-1, or catalase were enumerated in 20 random fields/tissue section (n = 6 mice/treatment group). Data are mean ± SE of positively stained cells per field. Data were analyzed using an unpaired t test.
a
Significantly (p ≤ 0.05) different from CTL.