Fig. 7. Effects of loss of FXR on NM-induced increases in expression of STAT6 and CD163.

Lung sections prepared 14 d and 28 d after administration of PBS (CTL) or NM to male wild-type (WT) and FXR^−/− mice were stained with antibodies to STAT6 and CD163. Binding was visualized using a peroxidase DAB substrate kit. Arrows indicate lung macrophages. Representative sections from 3–5 mice/treatment group are shown. Original magnification, 40×.