Table 1.
Baseline characteristics
| All | All patients | n1 | Non-myocardial injury group (n = 1048) | n2 | myocardial injury group (n = 78) | P* | |
|---|---|---|---|---|---|---|---|
| Gender (%) | 723(64.2%) | 667(63.6%) | 56(71.8%) | 0.147 | |||
| Age (years) | 1126 | 62.6 ± 11.9 | 1048 | 62.0 ± 11.7 | 78 | 71.0 ± 11.1 | < 0.001 |
| BMI (kg/m2) | 1109 | 23.4 ± 3.4 | 1034 | 22.4 ± 3.3 | 75 | 22.3 ± 3.8 | 0.748 |
| History | |||||||
| Smoking | 1126 | 0.003 | |||||
| Never smoking | 996(88.5%) | 928(88.5%) | 68(87.2%) | ||||
| Used to smoke | 115(10.2%) | 110(10.5%) | 5(6.4%) | ||||
| Current smoking | 15(1.3%) | 10(1.0%) | 5(6.4%) | ||||
| CAD | 85(7.5%) | 65(6.2%) | 20(25%) | < 0.001 | |||
| PCI history | 33(2.9%) | 27(2.6%) | 6(7.7%) | 0.025 | |||
| CABG history | 1(0.1%) | 0 | 1(1.3%) | 0.069 | |||
| Hypertension | 248(22.0%) | 215(20.5%) | 33(42.3%) | < 0.001 | |||
| Atrial fibrillation | 11(0.9%) | 7(0.7%) | 4(5.1%) | 0.005 | |||
| Diabetes mellitus | 113(10.0%) | 98(9.4%) | 15(19.2%) | 0.005 | |||
| Insulin dependent | 17(1.5%) | 11(1.0%) | 6(7.7%) | < 0.001 | |||
| Chronic renal failure | 6(0.5%) | 5(0.5%) | 1(0.3%) | 0.351 | |||
| Dialysis | 1(0.1%) | 0 | 1(1.3%) | 0.069 | |||
| Medical treatment | 1126 | ||||||
| Aspirin | 24(2.1%) | 21(2.0%) | 3(3.8%) | 0.496 | |||
| Clopidogrel | 29(2.6%) | 25(2.4%) | 4(5.1%) | 0.269 | |||
| Anticoagulation | 22(2.0%) | 15(1.4%) | 7(9.0%) | < 0.001 | |||
| β-blocker | 34(3.0%) | 27(2.6%) | 7(9.0%) | 0.004 | |||
| ACE inhibitor/ARB | 75(6.7%) | 64(6.1%) | 11(14.1%) | 0.006 | |||
| ARNI | 2(0.2%) | 2(0.2%) | 0 | 1 | |||
| CCB | 110(9.8%) | 98(9.4%) | 12(15.4%) | 0.083 | |||
| Statins | 40(3.6%) | 35(3.3%) | 5(6.4%) | 0.273 | |||
| Diuretic | 20(1.8%) | 15(1.4%) | 5(6.4%) | 0.006 | |||
| Metformin | 41(3.6%) | 35(3.3%) | 6(7.7%) | 0.096 | |||
| Chemotherapy | 148(13.1%) | 136(13.0%) | 12(15.4%) | 0.544 | |||
| Radiation therapy | 21(1.9%) | 21(2.0%) | 0 | 0.408 | |||
| LEE Index | 1126 | < 0.001 | |||||
| 0 | 993(88.2%) | 943(90.0%) | 50(64.1%) | ||||
| 1 | 112(9.9%) | 90(8.6%) | 22(28.2%) | ||||
| ≥ 2 | 21(1.9%) | 15(1.4%) | 6(7.7%) | ||||
| NYHA class II-IV | 14(1.2%) | 10(1.0%) | 4(5.1%) | 0.007 | |||
| Radical operation | 1006(89.3%) | 951(90.7%) | 55(71.4%) | < 0.001 | |||
| HR (beats per min) | 1125 | 80.4 ± 12.9 | 1047 | 80.4 ± 13.0 | 78 | 80.1 ± 11.9 | 0.868 |
| SBP (mmHg) | 1124 | 126.1 ± 18.3 | 1046 | 125.8 ± 18.1 | 78 | 130.7 ± 20.0 | 0.021 |
| DBP (mmHg) | 1124 | 76.9 ± 10.7 | 1046 | 77.0 ± 10.7 | 78 | 75.4 ± 10.4 | 0.184 |
Continuous variables are expressed as means ± standard deviation. Categorical variables are expressed as frequencies (percentage)
BMI, body mass index; CAD, coronary artery disease; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCB, calcium channel blocker; ANRI, angiotensin receptor neurolysin inhibitors; NYHA, New York Heart Association; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure
*Significance of the differences between the patients with and without myocardial injury