Table 7.
Overview of Questionnaires, Interviews, or Clinical Examinations in the Danish Twin Registry and Biobank
| Survey | Year of Survey | Birth Cohorts (Year of Birth) | Number of Participants | Information |
|---|---|---|---|---|
| Omnibus I | 1994 | 1953–1982 | 29,433 | Questionnaire on health and diseases such as diabetes, asthma or other symptoms related to the airways, eczema, hay fever, rheumatic diseases, headaches, migraine, epilepsy, fever cramps, back pain, inflammatory bowel diseases, thyroid disorders, anorexia, other long lasting diseases, fertility, and medication use. Lifestyle related factors such as physical activity, eating habits, weight, height, and body figure Family relations and sociodemographic factors |
| Omnibus II | 2002 | 1931–1982 | 34,943 | Questionnaire on health and diseases such as diabetes, osteoporosis, thyroid disorders, rheumatic disorders, epilepsy, heart diseases, migraine, back pain and disorders of the back, asthma and other symptoms from the airways, eczema and other allergic disorders, disorders of the ear, and speech disorders. Lifestyle related factors such as physical activity, weight, height, body figure, smoking, and alcohol consumption. Family relations and sociodemographic factors |
| LSADT | 1995 | 1892–1919 | 2401 | Interview on health such as diabetes, osteoporosis, osteoarthritis, rheumatoid arthritis, gout, chronic bronchitis, tuberculosis, asthma or other symptoms from the airways, disorders of the eye, meningitis, Parkinson´s disease, epilepsy, migraine, cancer, cardiovascular diseases, kidney diseases, thyroid disorders, fractures, gallstones, jaundice, mental disorders, symptoms of depression, problems with urination, fainting, back pain, menopause, sleep, physical abilities and medication use. Lifestyle related factors such as activities of daily living, weight, height, smoking, and alcohol consumption. Personality, mental wellbeing, family and social relations and sociodemographic factors. Cognitive tests (Mini Mental State Examination). From 1999 onwards, a short physical performance test involving measurements of chair stand, handgrip strength and lung function was included |
| 1997a (follow-up) | 1896–1923 | 2172 | ||
| 1999a (follow-up) | 1899–1928 | 2709 | ||
| 2001a (follow-up) | 1901–1930 | 2448 | ||
| 2003 (follow-up) | 1901–1930 | 1844 | ||
| 2005 (follow-up) | 1901–1930 | 1372 | ||
| 2007 (follow-up) | 1910–1923 | 121 | ||
| MADT | 1998 | 193–1952 | 4314 | Same questionnaires and examinations as LSADT (with a some exceptions) |
| 2008–2011 (follow-up) | 1931–1952 | 2400 | Follow-up questionnaire and examination | |
| MIDT | 2008–2011 | 1931–1969 (who were not in MADT) | 10,276 | Same questionnaires and examinations as LSADT (with a some exceptions) |
| GENIMAKAR | 1998 | 1931–1952 | 1512 | Questionnaire on diseases in the family, prenatal smoking exposure, and birth characteristics. Health such as symptoms or diseases of the airways, eyes, nose, neck, ears, cardiovascular system and medication use. Lifestyle related factors such as physical activity, weight, and smoking. Family relations and sociodemographic factors. Clinical examination including an oral glucose tolerance test, a maximal bicycle test, body composition determined by bio impedance, electrocardiogram, test of lung function, blood pressure, waist and hip circumference, weight, and height |
| 2010–2012 (follow-up) | 1931–1952 | 1145 | Questionnaire on health and diseases such as diabetes, cardiovascular diseases, menstruation, menopause, and medication use. Lifestyle related factors such as physical activity, weight, and smoking. Family relations, education, work, and well-being. Clinical examination including electrocardiogram, blood pressure, body composition, test of lung function, and various anthropometric measures |
Notes: Modified table from Pedersen DA, Larsen LA, Nygaard M et al. The Danish Twin Registry: An Updated Overview. Twin research and human genetics: the official journal of the International Society for Twin Studies. 2019;22(6):499–507. © The Author(s) 2019. Adapted with permission.56 Abbreviations: GENIMAKAR, the Importance of Genes, Familiar and Common Environment for the Development of Insulin Resistance, Abdominal Adiposity and Cardiovascular Risk Factors; LSADT, Longitudinal Study of Aging Danish Twins; MADT, Middle Age Danish Twins; MIDT, MIddle age Danish Twins. aAdditional cohorts were added in 1997, 1999 and 2001; twins aged 73–76 years were enrolled in 1997 and twins aged >70 years at the beginning of 1999 and 2001 were enrolled in these years.