Table 1.
Demographic characteristics and clinical features of the BECTS patients and healthy controls (mean ± SD).
| Clinical Features | Drug-Naïve (n = 22) | Medicated (n = 22) | HCs (n = 23) | p Value |
|---|---|---|---|---|
| Age (year) | 9.11 ± 1.86 | 9.68 ± 1.73 | 10.09 ± 2.86 | 0.343 a |
| Sex (male/female) | 11:11 | 16:6 | 16:7 | 0.233 b |
| Age at onset (year) | 8.64 ± 1.82 | 8.10 ± 2.06 | - | 0.350 c |
| Duration (month) | 6.58 ± 7.61 | 20.82 ± 11.82 | - | <0.05 c |
| EEG lateralization | 9 L/3 R/10 B | 6 L/7 R/9 B | - | 0.324 b |
| Number of seizures (count) | 2.86 ± 1.35 | 4.14 ± 2.10 | - | <0.05 c |
| Frequency of seizures (counts/year) | 2.55 ± 1.01 | 2.89 ± 1.50 | - | 0.381 c |
| VIQ | 84.00 ±7.35 | 82.41 ± 7.43 | 98.17 ± 6.04 | <0.001 a |
| PIQ | 95.00 ± 10.71 | 93.18 ± 12.12 | 110.87 ±7.23 | <0.001 a |
| FSIQ | 88.09 ± 8.66 | 86.13 ± 9.41 | 105.39 ± 6.04 | <0.001 a |
Abbreviations: BECTS, benign childhood epilepsy with centrotemporal spikes; SD, standard deviation; drug-naïve, unmedicated benign epilepsy with centrotemporal spikes; medicated, medicated benign epilepsy with centrotemporal spikes; HCs, healthy controls; EEG, electroencephalogram; L, left; R, right; B, bilateral; VIQ, verbal intelligence quotient; PIQ, performance intelligence quotient; FSIQ, full-scale intelligence quotient; ANOVA, analysis of variance. Superscripts indicate statistical test: a ANOVA; b chi-squared test. c two-sample t test.