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. 2023 Feb 5;24(4):3144. doi: 10.3390/ijms24043144

Table 4.

Ki for purines on the transport of [3H]-adenosine by TvxNT3.

Ki
AVG SEM n ΔG0 δ(ΔG0)
Adenosine 1.41 0.35 3 −33.38
Guanosine 1.37 0.13 3 −33.45 0.07
Inosine 0.18 0.05 3 −38.46 5.08
2′-deoxyadenosine 1.06 0.29 3 −34.1 0.70
5′-deoxyadenosine 1.10 0.12 3 −34.0 0.63
Cordycepin 8.6 1.4 3 −28.91 −4.47
Tubercidin 287 55 3 −20.21 −13.17
Nebularine 4.6 1.1 4 −30.4 −2.94
6-thioinosine 4.03 0.78 4 −30.8 −7.7
3-deazainosine 33.0 17.4 4 −25.6 −12.9
Adenine 2.43 0.14 2 −32.04 −1.34
Hypoxanthine 1.75 0.17 3 −32.85 −7.45
Uridine 720 110 3 −17.93 −15.45
Thymidine 603 51 3 −18.37 −15.01

IC50 values obtained were converted to Ki based on the Km of adenosine. See legends to Table 1 and Table 3 for further information.