ALT	Alternative lengthening of telomere
ChIP-on-Chip	Immunoprecipitation on chip
DDR	DNA damage response
DN	Dominant negative
ER	Endoplasmic reticulum
ES cells	Early-stage p53S/++Ras cells, senescent cells
GOF	Gain of function
IF	Immunofluorescence staining
LFL	Li–Fraumeni like
LFS	Li–Fraumeni syndrome
LOF	Loss of function
LOH	Loss of heterozygosity
LS cells	Late-stage p53S/++Ras cells, which bypassed the OIS
MEFs	Mouse embryonic fibroblasts
OIS	Oncogene-induced senescence
p53S	p53N236S
PDAC	Pancreatic ductal adenocarcinoma
PDH	Pyruvate dehydrogenase
PGC–1α	PPARγ coactivator
PPARγ	Peroxisome proliferator-activated receptor γ
ROS	Reactive oxygen species
SCID	Severe combined immune deficiency
WT	Wild type