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. 2023 Feb 15;13(2):335. doi: 10.3390/jpm13020335

Figure 2.

Figure 2

Effect of Canrenoic Acid and Spironolactone on the Action Potential parameters of DSC2 hiPSC−CM. (A) Raw traces of spontaneous AP in the control condition (black) (n = 14), mutated DSC2 (red) (n = 13), after incubation of 10 nM CA (green) (n = 18), and after incubation of 20 μM SP (blue) (n = 15). (B) Values of spontaneous frequency and (C) values of action potential duration at 90% repolarization. (D) Percentage of the number of cells presenting aberrant electrical events. Results are shown with the median and 95% confidence interval. The stars * correspond to the difference from the control. ns not statically significant, * p < 0.05, ** p < 0.01 (Kruskal–Wallis test).