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. 2023 Feb 16;15(2):551. doi: 10.3390/v15020551

Figure 2.

Figure 2

Quantitative immunohistochemical analysis for specific antibodies for immune cells in Z3, Z2, Z1 and PT cells in hepatic parenchyma of squirrel monkeys (Saimiri spp.) infected with YFV. Circles represent areas expressing higher immunostaining cells in different hepatic areas. (A) Expression of S100. (F) Immunostaining for S100 in Kupffer cells (F-Z3), inflammatory infiltrate (F-Z2), hepatocytes (F-Z1) and bile duct (F-PT). (B) Expression of CD11b. (G) Immunostaining for CD11b macrophages in inflammatory infiltrate (G-Z3), (G-Z2), (G-Z1), (G-PT). (C) Expression of CD57 NK cell. (H) Immunostaining for CD57 in inflammatory infiltrate in all hepatic compartments (H-Z3), (H-Z2), (H-Z1), (H-PT). (D) CD4 expression. (I) Immunostaining for CD4 T lymphocyte in the inflammatory infiltrate in all acini areas (I-Z3), (I-Z2), (I-Z1), (I-PT). (E) Expression of CD20 (B cell). (J) Absence of Immunostaining for CD20 in all acini areas (J-Z3), (J-Z2), (J-Z1), (J-PT). (E–J) obtained after 6 dpi.