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. 2023 Feb 16;15(2):551. doi: 10.3390/v15020551

Figure 5.

Figure 5

Quantitative immunohistochemical analysis of selected pro- inflammatory cytokines in zones Z3, Z2, Z1 and PT in the hepatic parenchyma of squirrel monkeys (Saimiri spp.) infected with YFV. Circles represent areas expressing higher immunostaining cells in different hepatic areas. (A) IFN-γ expression. (F)-Immunostaining for IFN-γ in hepatocytes (F-Z3), and in inflammatory infiltrate (F-Z2), (F-Z1), (F-PT). (B) Expression of IFN-β. (G) Immunostaining for IFN-β in hepatocytes (F-Z3), (F-Z2) in inflammatory infiltrate, (F-Z1) in hepatocytes, (F-PT). (C) Expression of TNF-α. (H) Immunostaining for TNF-α in inflammatory infiltrate (F-Z3), (F-Z2), (F-Z1), (F-PT). (D) Expression of IL-8. (I) Immunostaining for IL-8 in hepatocytes (F-Z3), (F-Z2), (F-Z1), (F-PT). (E) Expression of IL-17. (J) Immunostaining for IL-17 in hepatocytes (J-Z3), (J-Z2), (J-Z1), (J-PT) in 6 dpi.