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Maximal endothelium-dependent vasorelaxation in response to acetylcholine for all groups (Panel A) and preincubated with L-arginine 10−3 M and nor-NOHA 10−5 M in young WT, old WT and old G6PD-Tg (Panel B–D) in aortic rings. Results are expressed as % relaxation of acetylcholine 10−6 M and are the mean ± SD (n = 5–10 per group). ** p < 0.01 and * p < 0.05.
