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Changes in the glomerular phenotype in STZ-induced diabetic mice with or without febuxostat treatment. (a) Representative sections stained with periodic acid–Schiff reagent and representative immunohistochemical staining for TGF-β1 and type IV collagen (original magnification 400×). (b–d) Quantitative analyses of the results for mesangial fractional area (%), TGF-β1 and type IV collagen (fold) *** p < 0.001 vs. other groups.
