Table 1.
Physical and biochemical parameters of the four groups at the end of the 8-week experimental period.
| Cont | Feb | STZ | STZ + Feb | |
|---|---|---|---|---|
| BW (g) | 29.6 ± 0.8 | 27.0 ± 2.1 | 22.2 ± 2.0 ***,†† | 22.6 ± 2.6 ***,†† |
| Food intake (g/day) | 3.86 ± 0.20 | 3.20 ± 0.33 | 5.60 ± 0.13 ***,††† | 6.17 ± 0.38 ***,††† |
| Water intake (mL/day) | 6.33 ± 1.04 | 4.53 ± 0.23 | 23.4 ± 0.88 ***,††† | 24.2 ± 2.46 ***,††† |
| KW/BW(g/g × 100) | 0.7 ± 0.07 | 0.6 ± 0.06 | 0.9 ± 0.02 *,†† | 0.7 ± 0.1 ‡ |
| FBS (mg/dL) | 180.0 ± 22.3 | 172.8 ± 25.3 | 681.0 ± 155.2 *** | 489.9 ± 39.0 ***,†† |
| HbA1c (%) | 4.23 ± 0.31 | 4.16 ± 0.32 | 11.3 ± 1.32 ***,††† | 10.1 ± 1.48 ***,††† |
| Serum Cr (mg/dL) | 0.08 ± 0.05 | 0.08 ± 0.04 | 0.07 ± 0.05 | 0.04 ± 0.05 |
Abbreviations: STZ—streptozotocin; KW—kidney weight; BW—body weight; FBS—fasting blood glucose; HbA1c—Hemoglobin A1c; Cr—creatinine. * p < 0.05, and *** p < 0.001 compared with Cont groups, †† p < 0.01 and ††† p < 0.001 compared with Feb groups, ‡ p < 0.05 compared with STZ groups.