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. 2023 Jan 24;11(2):111. doi: 10.3390/toxics11020111

Table 2.

Inhalation dose reference exposure (RFC) and cancer inhalation unit risk for the characterized VOCs.

Agent RFC (mg m−3) Cancer Slop Factor (mg kg−1 day−1) USEPA/IARC Class Reference
Benzene 0.03 0.029 A IRIS a
Toluene 5 IRIS
Ethylbenzene 1 0.0087 2B IRIS
m,p-Xylene 0.1 IRIS
Styrene 1 5.7 × 10−4 2B CEP b
n-Hexane 0.7 IRIS
n-Heptane 0.4 IRIS
n-Nonane 0.02 IRIS
Trichloroethylene 0.002 1.1 × 10−2 2A IRIS
Tetrachloroethylene 0.04 2.07 × 10−2 2A IRIS
n-Butyl acetate 1.429 WHO c
n-Octane 1.111 MHLW d
n-Decane 0.836 Sagunski and Mangelsdorf [29]
Dichlorofluoromethane 0.330 IRIS
Acetone 56 OECD e

a IRIS: Integrated Risk Information System from USEPA. b CEP: Cumulative Exposure Project from USEPA. c WHO: World Health Organization. d MHLW: Ministry of Health, Labor, and Welfare. e OECD: Organization for Economic Co-operation and Development.