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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Nat Genet. 2023 Jan 12;55(2):209–220. doi: 10.1038/s41588-022-01276-9

Extended Data Fig. 5. ClueGO analysis using the MCD genes result identifies the biological processes and molecular pathways.

Extended Data Fig. 5

The main cluster is related to TOR signaling, regulation of cell-matrix adhesion, regulation of focal adhesion assembly, and artery morphogenesis. Notably, there are also isolated clusters that were not covered in previous studies, for example, cardiac muscle cell contraction, calcium ion import, and protein localization to the synapse. Corrected p-value with Bonferroni step down was reflected in node size (two-sided hypergeometric test, Large: p < 0.0005, medium: p < 0.005, small: p < 0.05). All p-values are in Supplementary Table 9.