Figure 4.
Effect of magnesium sulfate on serum corticosterone levels in rats exposed to chronic restraint stress (CRS). Administration of magnesium sulfate attenuated the increased serum corticosterone levels invoked by CRS [F (3, 20) = 30.08, p < 0.0001]. Values are expressed as the mean of 6 rats ± standard deviation (S.D.). Statistical analysis was applied using one-way ANOVA followed by Tukey’s post-hoc test. Significant differences versus control animals are denoted by * p < 0.05, or **** p < 0.001. Significant differences versus CRS group are denoted by #### p < 0.001. CRS, chronic restraint stress; MgSO4, magnesium sulfate.