Table 1.
Characteristics of individuals without and with mood disorders enrolled in this study; n = 40 in either group.
| Feature a | No Mood Disorders | Mood Disorders |
|---|---|---|
| Age (years) | 74.9 ± 7.3 | 76.2 ± 8.6 |
| Gender (M/F) | 18/22 | 14/26 |
| BMI (kg/m2) | 23.8 ± 1.9 | 22.4 ± 2.3 |
| CRP (mg/L) | 1.83 ± 0.33 | 3.64 ± 2.83 |
| AST (U/L) | 16.4 ± 3.7 | 19.1 ± 6.2 |
| ALT (U/L) | 16.1 ± 5.2 | 21.2 ± 8.9 |
| TSH (µIU/mL/L) | 2.07 ± 0.92 | 1.68 ± 1.22 |
| HbA1c (mmol/mol) | 36.3 ± 3.4 | 1.68 ± 1.22 |
| Creatinine (mg/dL) | 0.75 ± 0.23 | 0.86 ± 0.21 |
| GFR (mL/min) | 98.6 ± 10.7 | 89.1 ± 10.3 |
| ISI score | 9.6 ± 1.19 | 19.7 ± 6.2 *** |
| HAM-D score | 7.01 ± 1.12 | 20.8 ± 4.26 *** |
| TRP (mg daily) | 1256 ± 193 | 806 ± 174 *** |
| TRP (mg/body weight daily) | 21.2 ± 4.23 | 12.5 ± 3.96 *** |
a average ± SD (standard deviation), BMI—body mass index, CRP—C-reactive protein, FC—faecal calprotectin, AST—aspartate aminotransferase, ALT—alanine aminotransferase, TSH—thyroid-stimulating hormone, HbA1c—glycated hemoglobin, GFR—glomerular filtration rate; ISI—Insomnia Severity Index; HAM-D—Hamilton Depression Rating Scale; TRP—tryptophan intake; differences between groups were assessed by Student’s t-test, ***—p < 0.001.