Table 1.

Incidence of vascular pathologies assessed from fundus and optical coherence tomography (OCT) images.

Pathology	Timepoint	Incidence per Treatment Group (Number of Animals and Percentage of Total Number)
		Vehicle (n = 8)	Tonabersat (n = 12)
Vessel dilation	Day 2	8 (100%)	2 (16.7%) ****
Vessel tortuosity	Day 2	7 (87.5%)	4 (33.3%) ****
Vessel beading	Day 2	7 (87.5%)	6 (50%) ****
Hyperreflective foci	Day 2	3 (37.5%)	0 (0%) ****
Sub-retinal fluid accumulation	Day 7	2 (25%)	0 (0%) ****

Statistical analyses were carried out using the Fisher’s exact test. **** p < 0.0001.