Figure 2.

Experimental vaccines tested for various CVBs in the preclinical models. Several vaccine platforms shown with the upper-case text outside the big circle have been used to evaluate the efficacy of CVB vaccines in various preclinical models. While vaccines against CVB3 have been tested by using all the indicated approaches, killed vaccines have been tested for all six CVB serotypes, whereas VLP vaccines were tested only for CVB1, CVB3, and CVB5. The figure was created using biorender.com.