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. 2023 Feb 15;24(4):3886. doi: 10.3390/ijms24043886

Table 1.

Gell and Coombs classification of hypersensitivity reactions.

Type I IgE antibody-mediated reactions, e.g., anaphylaxis
Type II Antibody-mediated cytotoxic reactions, e.g., hemolytic anemia, thrombocytopenia, blood transfusion reactions
Type III Immune complex-mediated hypersensitivity, e.g., serum sickness, vasculitis
Type IV Delayed T cell-mediated responses, e.g., allergic contact dermatitis, maculopapular exanthema, erythema multiforme, toxic epidermal necrolysis, Drug-induced hypersensitivity syndrome (DiHS), hypersensitivity pneumonitis